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Toxoplasma gondii & Human Phenotype

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Toxoplasmosis as a cause of repeated abortion

October 29, 1995
Sahwi, S. Y., Zaki, M. S., Haiba, N. Y., Elsaid, O. K., Anwar, M. Y., AbdRabbo, S. A.
Asia-Oceania Journal of Obstetrics and Gynaecology 1995; 21: 145-148
Click for abstract
The extent to which toxoplasmosis causes habitual abortion is still controversial. The present study was carried out on 100 cases of repeated abortions, and 40 multiparous pregnant women at 20th week gestation as a control. Tests for the presence of toxoplasma IgG and/or IgM antibodies were done for both groups. It was found that 19% of the selected cases, and 7.5% of the control were seropositive for IgM. The difference was statistically insignificant, therefore acute toxoplasmosis, most probably, is not related to habitual abortions, whereas 37% of the selected cases and only 10% of the control group were seropositive at high dilution for IgG antibody, this statistical significant difference indicates that chronic toxoplasmosis, most probably is a significant cause of repeated abortion. Also it has been found that toxoplasmosis has a significant relation to abortion at first trimester.

Tagged: abortion, adult, animals, antibodies, female, Habitual/*parasitology, humans, immunoglobulin G/blood, Immunoglobulin M/blood, pregnancy, protozoan/blood, Toxoplasma/immunology, Toxoplasmosis/*complications/diagnosis

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