Effects of Toxoplasma on human behavior
Flegr, J.
Schizophrenia Bulletin 2007; 33: 757-760
Click for abstract
Although latent infection with
Toxoplasma gondii
is among
the most prevalent of human infections, it has been gener-
ally assumed that, except for congenital transmission, it is
asymptomatic. The demonstration that latent
Toxoplasma
infections can alter behavior in rodents has led to a recon-
sideration of this assumption. When infected human adults
were compared with uninfected adults on personality ques-
tionnaires or on a panel of behavioral tests, several differ-
ences were found. Other studies have demonstrated reduced
psychomotor performance in affected individuals. Possible
mechanisms by which
T. gondii
may affect human behavior
include its effect on dopamine and on testosterone.