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Toxoplasma gondii & Human Phenotype

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psychiatric-related disease

Epidemiological evidences from China assume that psychiatric-related diseases may be associated with Toxoplasma gondii infection

January 4, 2007
Zhu, S., Guo, M. F., Feng, Q. C., Fan, J. M.,
Neuroendocrinology Letters, 2007, 28: 115-120
Click for abstract
In recent years, the effect of Toxoplasma gondii infection on psychiatric-related aspects has been increasingly recognized. T gondii has a high affinity for brain tissue where tachyzoites may form tissue cysts and persist life long. In recent years, 15 serological surveys about T gondii infection and psychiatric diseases have been carried out in different areas in China. Studies showed that the prevalence of antibodies against T gondii in psychotic patients was much higher than in normal persons; statistically differences were significant. Studies also reported that raising cats or enjoying the habit of eating raw or under cooked meet were potential risk factors for the infection of T gondii. The epidemiological and serological evidence support the hypothesis that some psychiatric diseases such as schizophrenia or mental retardation might be linked to T gondii infection.

Tagged: 1st-episode schizophrenia, antibodies, behavior, cats, host, novelty seeking, parasites, personality changes, psychiatric-related disease, rattus-norvegicus, toxoplasmosis

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