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Toxoplasma gondii & Human Phenotype

Compendium of Known Effects and Ongoing Research

invitro

Anti-Toxoplasma gondii antibodies in haemodialysis patients with chronic renal failure

October 30, 2003
Yazar, S., Demirtas, F., Yalcin, A., Yaman, O., Tokgoz, B., Utas, C., Sahin, I.
Yonsei Medical Journal 2003; 44: 288-292
Click for abstract
This study aimed to determine the prevalence of anti-Toxoplasma gondii antibodies in haemodialysis patients with chronic renal failure (CRF). Methods: One hundred and seventy three haemodialysis patients, and 40 healthy controls, were studied for the prevalence of anti-Toxoplasma gondii antibodies by a micro enzyme-linked immunosorbent assay (ELISA). Anti-T gondii IgG antibodies were detected in 97 (56.06%) haemodialysis patients and 8 (20%) controls with a statistical significance. In addition, anti-T. gondii IgM antibodies were detected in 1.73% of patients, but none of the controls. In conclusion, a high percentage of positivity for Toxoplasma antibodies in patients with CRF undergoing haemodialysis was noticed, thus parasitological surveys of CRF patients should be periodically performed to prevent the possible dissemination of toxoplasmosis through the dialysis procedure.

Tagged: chronic renal failure, elisa, haemodialysis, invitro, Toxoplasma gondii, uremia

Physical health

Infection, treatment and immune response in patients with bipolar disorder versus patients with major depression, schizophrenia or healthy controls

November 7, 2002
Hinze-Selch D.
Bipolar Disord 2002; 4 Suppl 1: 81-83
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Bipolar disorder is the least Studied among the three major psychiatric disorders of schizophrenia, major depression and bipolar disorder. Furthermore, investigations on infection and immunity in bipolar disorder make up only a small portion of the sparse research done on this disorder. However, there are reports that modulation of the immune system and certain infections might be associated with bipolar disorder and that there might be differences between bipolar and the other disorders. The purpose of this paper is to briefly review published data on these issues in bipolar versus the other disorders, and to present an ongoing clinical study on the putative involvement of infection with the parasite Toxoplasma gondii in these three major psychiatric disorders.

Tagged: bipolar disorder, blood mononuclear-cells, carbamazepine, disease, hiv-infection, immunity, in-vitro, infection, invitro, lithium, lymphocytes, secondary mania, sodium valproate, Toxoplasma gondii, valproate

Mental health

Topics

  • Behavior 105
  • Cognitive functions 64
  • Mental health 439
  • Morphology 6
  • Motor functions 10
  • Personality 36
  • Physical health 134
  • Reproduction 36
  • Reviews 40
  • Sensory functions 3
  • Uncategorized 2

Archives

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