diagnosis

The relationship between pediatric obsessive compulsive disorder and Toxoplasma gondii

February 1, 2020
Memik, N. C., Tamer, G. S., Unver, H., Gundogdu, O. Y.
Journal of Obsessive-Compulsive and Related Disorders 2015, 7: 24 - 28

Click for abstract

Prevalence and risk factors of Toxoplasma infection – an update in Malaysian pregnant women

January 30, 2020
Chemoh, W., Farhana, M. N. N., Azmi, M. A. N., Lay, K. S., Sawangjaroen, N., Tan, T. C., Chandramathi, S. R., Nissapatorn, V.
Tropical Biomedicine 2019, 36: 694 - 702

Click for abstract

Is Toxoplasma gondii infection a risk factor for leukemia? An evidence-based meta-analysis

October 6, 2016
Huang, Y., Chang, A. S., Wang, J. S., Zeng, X. Q.,
Medical Science Monitor 2016; 22.

Click for abstract

Seroprevalence and serointensity of latent Toxoplasma gondii in a sample of elderly adults with and without Alzheimer disease

October 3, 2016
Perry, C. E., Gale, S. D., Erickson, L., Wilson, E., Nielsen, B., Kauwe, J., Hedges, D. W.
Alzheimer Disease and Associated Disorders 2016; 30: 123-126

Click for abstract

Seroprevalence of Toxoplasma gondii infection among patients with non-schizophrenic neurodevelopmental disorders in Alexandria, Egypt

October 3, 2016
Shehata AI, Hassanein FI, Abdul-Ghani R
Acta Tropica 2016; 154: 155-159

Click for abstract

Influence of Toxoplasma gondii infection on symptoms and signs of premenstrual syndrome: A cross-sectional study.

September 4, 2016
Alvarado-Esquivel, C., Sanchez-Anguiano, L. F., Hernandez-Tinoco, J., Perez-Alamos, A. R., Rico-Almochantaf, Y. D., Estrada-Martinez, S., Vaquera-Enriquez, R., Diaz-Herrera, A., Ramos-Nevarez, A., Sandoval-Carrillo, A. A., Salas-Pacheco, J. M., Cerrillo-Soto, S. M., Antuna-Salcido, E. I., Liesenfeld, O., Guido-Arreola, C. A.
European Journal of Microbiology and Immunology 2016; 6: 298-305

Click for abstract

Seroprevalence of Toxoplasma gondii infection among patients with non-schizophrenic neurodevelopmental disorders in Alexandria, Egypt

May 28, 2016
Shehata, A. I., Hassanein, F. I., Abdul-Ghani, R.
Acta Tropica 2016; 154: 155-159

Click for abstract

Seroprevalence of Toxoplasma gondii infection among patients with non-schizophrenic neurodevelopmental disorders in Alexandria, Egypt

May 24, 2016
Shehata, A.I., Hassanein, F.I., Abdul-Ghani, R.
Acta Tropica 2016;154: 155-159

Click for abstract

Seroprevalence of Toxoplasma gondii infection in patients with Alzheimer’s disease

January 4, 2016
Rashno, M. M., Fallahi, S., Kheirandish, F., Bagheri, S., Kayedi, M. H., Birjandi, M.
Archives of Clinical Infectious Diseases 2016, 11: ARTN e37205 10.5812/archcid.37205

Click for abstract

Background: Toxoplasmosis is one of the most important diseases in humans and animals. Almost one-third of the human population around the world is infected with toxoplasmosis. The agent of this parasitic disease is a protozoan called Toxoplasma gondii (T. gondii) that causes encephalitis in people with suppressed immune systems and abortion, mental retardation and chorioretinitis in the fetus. Alzheimer's disease (AD) is the most important neurodegenerative disease. Objectives: Due to the high prevalence of toxoplasmosis in Iran and evidence on its impact on neurodegenerative diseases, this study was performed to evaluate the T. gondii infection in patients with AD. Patients and Methods: In this case-control study, after selection of alzheimer's patients (APs) referred to Imam Reza psychiatric hospital of Khorramabad, west of Iran, and healthy controls (each group consisted of 87 individuals), using the convenience sampling method and under the supervision of a neurologist, blood samples were taken during July 2014 and January 2015. The collected samples were transferred to the research laboratory of parasitology under cold chain storage and then, the serum samples were separated by centrifugation and were frozen at -20 degrees C until use. The T. gondii IgM and IgG specific antibodies were assessed in serum samples using commercial Enzyme Linked Immunosorbent Assay (ELISA) kits. Results: The overall prevalence of T. gondii infection in patients with AD and the control group, using ELISA assay, was obtained as 66.6% (58/87) and 56.32% (49/87), respectively (P = 0.99). In this study, there was no significant association between T. gondii infection and AD. On the other hand, no statistically significant difference was observed between the two groups in terms of infection with T. gondii (P = 0.99). Conclusions: Higher prevalence of T. gondii in patients with AD compared to controls showed the possible impact of this parasite in AD, which may exacerbate symptoms, and this requires special attention of specialists and patient families.

Is toxoplasmosis a potential risk factor for liver cirrhosis?

October 9, 2015
El-Henawy, A. A., Razik, A. A., Zakaria, S., Elhammady, D., Saudy, N., Azab, M. S.
Asian Pacific Journal of Tropical Medicine 2015; 8: 768-775

Click for abstract

The relationship between pediatric obsessive compulsive disorder and Toxoplasma gondii

October 6, 2015
Memik, N. C., Tamer, G. S., Unver, H., Gundogdu, O. Y.
Journal of Obsessive-Compulsive and Related Disorders 2015; 7: 24-28

Ocular toxoplasmosis past, present and new aspects of an old disease

October 30, 2014
Maenz, M., Schluter, D., Liesenfeld, O., Schares, G., Gross, U., Pleyer, U.
Progress in Retinal and Eye Research 2014; 39: 77-106

Click for abstract

Seroepidemiology of Toxoplasma gondii infection in drivers involved in road traffic accidents in the metropolitan area of Guadalajara, Jalisco, Mexico

October 10, 2013
Galvan-Ramirez, M. D., Sanchez-Orozco, L. V., Rodriguez, L. R., Rodriguez, S., Roig-Melo, E., Sanroman, R. T., Chiquete, E., Armendariz-Borunda, J.
In: Parasites & Vectors 2013;6:10.1186/1756-3305-6-294

Click for abstract

Background: The prevalence of toxoplasmosis in the general population of Guadalajara, Mexico, is around 32%. Toxoplasmosis can cause ocular lesions and slowing of reaction reflexes. Latent toxoplasmosis has been related with traffic accidents. We aimed to assess the prevalence of anti-Toxoplasma gondii antibodies and visual impairments related with traffic accidents in drivers from the metropolitan Guadalajara. Methods: We prospectively evaluated the prevalence of IgG and IgM anti-T. gondii antibodies in 159 individuals involved in traffic accidents, and in 164 control drivers never involved in accidents. Cases of toxoplasmosis reactivation or acute infection were detected by PCR in a subset of 71 drivers studied for the presence of T. gondii DNA in blood samples. Ophthalmologic examinations were performed in drivers with IgG anti-T. gondii antibodies in search of ocular toxoplasmosis. Results: Fifty-four (34%) traffic accident drivers and 59 (36%) controls were positive to IgG anti-T. gondii antibodies (p = 0.70). Among the 113 seropositive participants, mean anti-T. gondii IgG antibodies titers were higher in traffic accident drivers than in controls (237.9 +/- 308.5 IU/ml vs. 122.9 +/- 112.7 IU/ml, respectively; p = 0.01 by Student's t test, p = 0.037 by Mann-Whitney U test). In multivariate analyses, anti-T. gondii IgG antibody titers were consistently associated with an increased risk of traffic accidents, whereas age showed an inverse association. The presence of IgM-anti-T. gondii antibodies was found in three (1.9%) subjects among traffic accident drives, and in two (1.2%) controls. Three (4.2%) samples were positive for the presence of T. gondii DNA, all among seropositive individuals. No signs of ocular toxoplasmosis were found in the entire cohort. Moreover, no other ocular conditions were found to be associated with the risk of traffic accidents in a multivariate analysis. Conclusions: Anti-T. gondii antibody titers are associated with the risk of traffic accidents. We could not determine any association of ocular toxoplasmosis with traffic accidents. Our results warrant further analyses in order to clarify the link between toxoplasmosis and traffic accidents

Toxoplasma gondii & Human Phenotype

Compendium of Known Effects and Ongoing Research

The relationship between pediatric obsessive compulsive disorder and Toxoplasma gondii

Prevalence and risk factors of Toxoplasma infection – an update in Malaysian pregnant women

Is Toxoplasma gondii infection a risk factor for leukemia? An evidence-based meta-analysis

Seroprevalence and serointensity of latent Toxoplasma gondii in a sample of elderly adults with and without Alzheimer disease

Seroprevalence of Toxoplasma gondii infection among patients with non-schizophrenic neurodevelopmental disorders in Alexandria, Egypt

Influence of Toxoplasma gondii infection on symptoms and signs of premenstrual syndrome: A cross-sectional study.

Seroprevalence of Toxoplasma gondii infection among patients with non-schizophrenic neurodevelopmental disorders in Alexandria, Egypt

Seroprevalence of Toxoplasma gondii infection among patients with non-schizophrenic neurodevelopmental disorders in Alexandria, Egypt

Seroprevalence of Toxoplasma gondii infection in patients with Alzheimer’s disease

Is toxoplasmosis a potential risk factor for liver cirrhosis?

The relationship between pediatric obsessive compulsive disorder and Toxoplasma gondii

Ocular toxoplasmosis past, present and new aspects of an old disease

Seroepidemiology of Toxoplasma gondii infection in drivers involved in road traffic accidents in the metropolitan area of Guadalajara, Jalisco, Mexico

Seroprevalence of Toxoplasma gondii infection in female sterility patients in China

Maternal exposure to toxoplasmosis and risk of schizophrenia in adult offspring

Toxoplasma infection in systemic lupus erythematosus mimicking lupus cerebritis

Tumours of the brain and presence of antibodies to Toxoplasma gondii

Toxoplasmosis and lupus. A review of the literature apropos of 4 cases