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Toxoplasma gondii & Human Phenotype

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chronic renal failure

Anti-Toxoplasma gondii antibodies in haemodialysis patients with chronic renal failure

October 30, 2003
Yazar, S., Demirtas, F., Yalcin, A., Yaman, O., Tokgoz, B., Utas, C., Sahin, I.
Yonsei Medical Journal 2003; 44: 288-292
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This study aimed to determine the prevalence of anti-Toxoplasma gondii antibodies in haemodialysis patients with chronic renal failure (CRF). Methods: One hundred and seventy three haemodialysis patients, and 40 healthy controls, were studied for the prevalence of anti-Toxoplasma gondii antibodies by a micro enzyme-linked immunosorbent assay (ELISA). Anti-T gondii IgG antibodies were detected in 97 (56.06%) haemodialysis patients and 8 (20%) controls with a statistical significance. In addition, anti-T. gondii IgM antibodies were detected in 1.73% of patients, but none of the controls. In conclusion, a high percentage of positivity for Toxoplasma antibodies in patients with CRF undergoing haemodialysis was noticed, thus parasitological surveys of CRF patients should be periodically performed to prevent the possible dissemination of toxoplasmosis through the dialysis procedure.

Tagged: chronic renal failure, elisa, haemodialysis, invitro, Toxoplasma gondii, uremia

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