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Toxoplasma gondii & Human Phenotype

Compendium of Known Effects and Ongoing Research

2nd

Sex-dependent toxoplasmosis-associated differences in testosterone concentration in humans

January 9, 2008
Flegr, J., Lindová, J., Kodym, P.
Parasitology 2008; 135: 427-431
Click for abstract
Several lines of indirect evidence suggest that subjects with latent infection of the coccidian parasite Toxoplasma gondii have a higher concentration of testosterone than uninfected controls. Here, we searched for direct evidence of latent toxoplasmosis-associated differences in testosterone concentration among a Population of 174 female and 91 male students screened for Toxoplasma infection. We have found Toxoplasma-infected men to have a higher concentration of testosterone and Toxoplasma -infected women to have a lower concentration of testosterone than Toxoplasma -free controls. The opposite direction of the testosterone shift in men compared to women can explain the observed gender specificity of behavioural shifts in Toxoplasma- infected subjects.

Tagged: 2nd, 4th digit ratio, androgens, behaviour, complement-fixation, Dopamine, gender, gondii, hormones, human-behavior, infection, latent toxoplasmosis, manipulation., parasites, Toxoplasma

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