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Toxoplasma gondii & Human Phenotype

Compendium of Known Effects and Ongoing Research

permutation test

Influence of latent ‘asymptomatic’ toxoplasmosis on body weight of pregnant women

September 26, 2005
Flegr J., Hrdá S., Kodym P
Folia Parasitologica 52: 199-204, 2005
Click for abstract
The latent toxoplasmosis is usually considered to be asym ptomatic, however, this paradi gm has never been rigorously tested. Here we searched for symptoms of de terioration of physical health (decrease of weight) in infected people by analysis o f clinical records of 758 women tested for toxoplasmosis in the 16th week of gravidity. Toxoplasma -positive women have a lower body weight in the 16th week of gravidity (p = 0.02) than Toxoplasma -negative women. Moreover, a negative correlation be- tween weight and the duration of toxoplasmosis was found in a subset of 174 Toxoplasma -positive women (p = 0.04), suggesting that slow and cumulative effects of latent toxoplasmosis, rather than a transient eff ect of acute toxoplasmosis, are responsibl e for the decreased weight of infected subjects. Longer duration of gr avidity estimated from the date of last menstruation in the set of Toxoplasma -positive women in the 16th week of gravidity estimated with ultrasonography (p = 0.04) suggests a possibility of retarded foetal growth in Toxoplasma -positive women. The prevalence of latent toxopl asmosis is extremely high. Therefore, even its mild symptoms such as the decreased body weight in Toxoplasma- positive pregnant women mi ght in fact indicate an unrecognized serious public health problem.

Tagged: gravidity, latent toxoplasmosis, Parasite, pathology, permutation test, Toxoplasma

Physical health

Changes in personality profile of young women with latent toxoplasmosis

September 26, 1999
Flegr, J., Havlícek, J.
Folia Parasitologica 1999; 46: 22-28
Click for abstract
Abstract. Latent toxoplasmosis is the most widesp read parasite infection in developed and developing countries. The prevalence of Toxoplasma gondii infection varies mostly between 20 to 80% in differe nt territories. This form of toxoplasmosis is generally considered to be asymptomatic. Recently published results, however, suggest that the personality profiles of infected subjects differ from those of uninfected controls. Th ese results, however, were obtained on non-standard populations (biologists or former acute toxoplasmosis patients). Here we studied the pers onality profiles of 191 young women tested for anti- Toxoplasma immunity during gravidity. The results showed that the differences between Toxoplasma -negative and Toxoplasma -positive subjects exits also in this sample of healthy women. The subjects with latent toxoplasmosis had higher intelligence, lower guilt proneness, and possibly al so higher ergic tension. The difference in several other factors (d esurgency/surgency, alaxia/protension, naiveté/shrewdness, and self- sentiment integration) concerned changes in the vari ances, rather than the mean values of the factors.

Tagged: behaviour, Cattell's questionnaire, ma nipulation hypothesis, permutation test, Toxoplasma gondii

Personality

Topics

  • Behavior 105
  • Cognitive functions 64
  • Mental health 439
  • Morphology 6
  • Motor functions 10
  • Personality 36
  • Physical health 134
  • Reproduction 36
  • Reviews 40
  • Sensory functions 3
  • Uncategorized 2

Archives

Recent articles

  • Mortality Patterns of Toxoplasmosis and Its Comorbidities in Tanzania: A 10-Year Retrospective Hospital-Based Survey February 6, 2020
  • The role of latent toxoplasmosis in the aetiopathogenesis of schizophrenia–the risk factor or an indication of a contact with cat? February 6, 2020
  • The Association between Toxoplasma gondii Infection and Risk of Parkinson’s Disease: A Systematic Review and Meta-Analysis February 6, 2020

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