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Toxoplasma gondii & Human Phenotype

Compendium of Known Effects and Ongoing Research

Cattell’s questionnaire

Correlation of duration of latent Toxoplasma gondii infection with personality changes in women

September 26, 2000
Flegr, J., Kodym, P.,Tolarová, V.
Biological Psychology 2000; 53: 57-68
Click for abstract
Many parasites induce characteristic changes in behavior of their hosts. In humans latent toxoplasmosis is associated with changes in personality profiles. It has been already shown that a decrease in superego strength is correlated with duration of toxoplasmosis in men. Here we studied changes in personality profiles with Cattell’s 16 PF questionnaire in Toxoplasma -infected women. The changes were measured as differences in personality factors between Toxoplasma -infected subjects and uninfected controls of the same age. The low-rate changes were studied in 230 women diagnosed with acute toxoplasmosis during past 14 years. The results showed the correlation between duration of toxoplasmosis and level of factors G (high superego strength) and Q3 (high strength of self sentiment). The high-rate changes were estimated by measuring the correlation between level of Toxoplasma -antibody titers (which rapidly decline after the end of acute phase of toxoplasmosis) and personality factors in an experimental set of 55 young mothers with latent toxoplasmosis. Again, certain factors, namely A (affectothymia), F (surgence), G (high superego strength), H (parmia), and L (protension), correlated with the length of the infection. We suggest that the parasite induced the changes in the personality profiles of the women because of our observation of an increasingly different personality profile over time between women with latent infection and controls. The same evidence questions the view that women with a particular personality profile are more prone to acquisition

Tagged: 16PF, behavior, Cattell's questionnaire, Human, manipulation hypothesis, Parasite, Toxoplasma gondii

Personality

Changes in personality profile of young women with latent toxoplasmosis

September 26, 1999
Flegr, J., Havlícek, J.
Folia Parasitologica 1999; 46: 22-28
Click for abstract
Abstract. Latent toxoplasmosis is the most widesp read parasite infection in developed and developing countries. The prevalence of Toxoplasma gondii infection varies mostly between 20 to 80% in differe nt territories. This form of toxoplasmosis is generally considered to be asymptomatic. Recently published results, however, suggest that the personality profiles of infected subjects differ from those of uninfected controls. Th ese results, however, were obtained on non-standard populations (biologists or former acute toxoplasmosis patients). Here we studied the pers onality profiles of 191 young women tested for anti- Toxoplasma immunity during gravidity. The results showed that the differences between Toxoplasma -negative and Toxoplasma -positive subjects exits also in this sample of healthy women. The subjects with latent toxoplasmosis had higher intelligence, lower guilt proneness, and possibly al so higher ergic tension. The difference in several other factors (d esurgency/surgency, alaxia/protension, naiveté/shrewdness, and self- sentiment integration) concerned changes in the vari ances, rather than the mean values of the factors.

Tagged: behaviour, Cattell's questionnaire, ma nipulation hypothesis, permutation test, Toxoplasma gondii

Personality

Induction of changes in human behaviour by the parasitic protozoan Toxoplasma gondii

September 26, 1996
Flegr, J., Zitková, Š., Kodym, P., Frynta, D.
Parasitology 1996; 113: 49 - 54
Click for abstract
Toxoplasma gondii, the coccidian parasite, is known to induce changes in the behaviour of its intermediate hosts. The high prevalence of this parasite in the human population (20-80%) offers the opportunity of studying the influence of the parasite on human behaviour by screening of a normal population. Two hundred and twenty-four men and one hundred and seventy women were tested for toxoplasmosis and their personality profiles were measured by Cattell's questionnaire. Highly significant differences between Toxoplasma infected and uninfected subjects were observed (p < 0.01). For men the factors G (low superego strength, p<0.02), and possibly L (protension), O (guilt proneness), and A (sizothymia) prevailed in infected subjects. For women the prevailing factors were A (afectothymia, p<0.01), and possibly L (alaxia) and N (shrewdness). To reveal whether toxoplasmosis induces personality factor-shifts or whether certain combinations of personality factors influence the probability of acquiring Toxoplasma infection, we examined the personality profiles of 164 male patients diagnosed with acute toxoplasmosis during the past 13 years. The existence of a positive correlation between the duration of latent toxoplasmosis and the intensity of superego strength decrease (p<0.02) suggested that the decrease of superego strength (the willingness to accept group moral standards) was induced by T. gondii infection.

Tagged: behaviour, Cattell's questionnaire, manipulation hypothesis, personality, Toxoplasma

BehaviorPersonality

Influence chronic toxoplasmosis on some personality factors

September 26, 1994
Flegr, J., Hrdy, I.
Folia Parasitologica 1994; 41: 122-126
Click for abstract
Abstract. An effect of parasites on host behaviour was tested on the toxoplasma-human model. Three hundred and thirty-eight (338) people were assessed with Cattell's personality questionnaire and then tested for Toxoplasma gondii infection with a delayed type hypersensitivity test for Toxoplasma. A highly significant correlation between chronic toxoplasmosis and two personality factors (G- Low Superego Strength and L- Protension) was found (p =0.0032 and 0.0020, respectively). A correlation of the intensity of the personality factor-shifts with the duration of the infection (estimated from antibody titer) suggests that toxoplasmosis induces the shift in human personality, rather than the personality factors G and L influence an acquisition rate of Toxoplasma gondii infection.

Tagged: behaviour, Cattell's questionnaire, manipulation hypothesis, personality factors, Toxoplasma, toxoplasmosis

Personality

Topics

  • Behavior 105
  • Cognitive functions 64
  • Mental health 439
  • Morphology 6
  • Motor functions 10
  • Personality 36
  • Physical health 134
  • Reproduction 36
  • Reviews 40
  • Sensory functions 3
  • Uncategorized 2

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Recent articles

  • Mortality Patterns of Toxoplasmosis and Its Comorbidities in Tanzania: A 10-Year Retrospective Hospital-Based Survey February 6, 2020
  • The role of latent toxoplasmosis in the aetiopathogenesis of schizophrenia–the risk factor or an indication of a contact with cat? February 6, 2020
  • The Association between Toxoplasma gondii Infection and Risk of Parkinson’s Disease: A Systematic Review and Meta-Analysis February 6, 2020

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